海洋渔业电子地图系统软件设计与实现

系统地介绍了海洋渔业电子地图系统软件EA2000的数据模型和主要功能的设计与实现，EA2000采用了面向对象的数据模型，紧密的矢栅数据接口，以及图层－地图－图集一体化数据组织管理方法，该软件具有开放的数据输入接口，图层创作的自动化和动态交互式编辑，双向查询检索，缩放漫游与多级比例尺联动显示，动态显示，对象信息自动显示，地理信息系统渔船动态监控管理，多媒体信息插入管理，互操作等功能。     

用剩余产量模型专家系统(CLIMPROD)评估东海鲐鲹鱼类最大持续产量

根据统计资料，利用剩余产量模型专家系统（CLIMPROD）对东海鲐鲹鱼类最大持续产量（MSY）作了评估分析。结果表明：东海鲐鲹鱼类合计分析时的MSY在34．5~44．2万吨之间，接种类分别评估时，鲐鱼的MSY为16．1万吨，蓝圆鲹为22．2万吨；按区域分析时，鲐鲹鱼东海北部群的MSY为12．5~13．2万吨，福建沿海群为20．1万吨。     

渔业资源管理目标定量确定的探讨

本文主要探讨渔业资源管理目标定量确定(包括渔业种类及其可捕规格和产量的确定)过程中常用的数学方法，并指出各种方法的应用范围。     

基于灰色预测模型对白城市未来五年居民需水量的预测

需水量是城市水资源的一个重要方面,预测城市居民需水量成为指导水资源合理配置的最重要的一项科技指标。本文以吉林省白城市2004～2013年的居民需水量数据为研究对象,比较不同维数的灰色GM（1,1）预测模型的误差,选择最优模型对白城市今后五年需水量进行预测分析,可以为水利部门分配水资源提供科学依据。     

宋庄镇创意休闲农业发展规划研究

创意休闲农业是一种新型创意产业,它以农业资源为基础。将都市型现代农业与文化相结合,通过深度拓展农业功能,融合农业、科技、文化、创新等于一体而发展形成的满足特定市场需求的新兴产业。该文以北京市通州区宋庄镇为例,分析了宋庄镇创意休闲农业的发展条件,探讨了未来宋庄镇创意休闲农业的发展思路和布局,为宋庄创意休闲农业的特色化、品牌化发展提供建议。     

Analysis of risk factors associated with bovine leukemia virus seropositivity within dairy and beef breeding farms in Japan: A nationwide survey

This cross-sectional study evaluated risk factors associated with farm-level bovine leukemia virus (BLV) seropositivity in 563 dairy and 490 beef farms throughout Japan. Twenty randomly selected cattle on each farm were serologically tested, and farm epidemiologiocal information was obtained through face-to-face interviews. Due to the large number of zero-prevalence dairy and beef farms, data analysis was performed using a zero-inflated negative binomial model, which revealed that the common risk factors associated with higher within-farm seroprevalence were past detection of clinical leukemia and presence of blood-sucking insects. Loose housing on dairy farms and direct contact between calves and adult cattle on beef farms were also identified as risk factors. With regard to farm-level presence of BLV, the presence of purchased cattle was found to be a risk factor in both sectors. Sending heifers to a common ranch was identified as an additional risk factor for dairy farms.     

Temporal associations between low body condition,lameness and milk yield in a UK dairy herd

Previous work has hypothesised that cows in low body condition become lame. We tested this in a prospective longitudinal study. Body condition score (BCS), causes of lameness and milk yield were collected from a 600-cow herd over 44-months. Mixed effect binomial models and a continuous outcome model were used to investigate the associations between lameness, BCS and milk yield. In total, 14,320 risk periods were obtained from 1137 cows. There were 1510 lameness treatments: the most common causes of lameness were sole ulcer (SU) (39%), sole haemorrhage (SH) (13%), digital dermatitis (DD) (10%) and white line disease (WLD) (8%). These varied by year and year quarter. Body condition was scored at 60-day intervals. BCS ranged from 1 to 5 with a mean of 2.5, scores were higher in very early lactation but varied widely throughout lactation; approximately 45% of scores were <2.5. The key finding was that BCS < 2.5 was associated with an increased risk of treatment for lameness in the following 0–2 months and >2–4 months for all causes of lameness and also specifically for SU/WLD lameness. BCS < 2.5 was associated with an increased risk of treatment for SH in the following 0–2 months but not >2–4 months. There was no such association with DD. All lameness, SU/WLD, SH and DD were significantly more likely to occur in cows that had been lame previously, but the effect of BCS was present even when all repeat cases of lameness were excluded from the analysis. Milk yield was significantly higher and fell in the month before treatment in cows lame with SU/WLD but it was not significantly higher for cows that were treated for DD compared with non-lame cows. These findings support the hypothesis that low BCS contributes to the development of horn related claw lameness but not infectious claw diseases in dairy cows. One link between low BCS and lameness is a thin digital cushion which has been proposed as a trigger for claw horn disease. Cows with BCS 2 produced more milk than cows with BCS 2.5, however, this was only approximately 100 kg difference in yield over a 305-day lactation. Given the increased risk of lameness in cows with BCS 2, the direct costs of lameness and the small variability in milk yield by BCS, preventing cows from falling to BCS < 2.5 would improve cow welfare and be economically beneficial.     

Murine xenograft model demonstrates significant radio-sensitising effect of liposomal doxorubicin in a combination therapy for Feline Injection Site Sarcoma

Therapy of cats suffering from feline injection site sarcomas (FISS) is still a challenging problem, as the recurrence rate after surgery is up to 70%. Four FISS-derived primary tumour cell lines and corresponding xenograft tumour mouse models were established to evaluate the efficacy of a concomitant chemo-/radiation therapy with doxorubicin. In vitro, strongly depending upon the timing of administration, pre-treatment with 0.25 µmol doxorubicin resulted in a significant enhancement of radiation-induced (3.5 Gy) tumour cell death. This result was confirmed in vivo, where only the combined chemo-/radiation therapy resulted in a significant reduction in tumour growth compared to the respective mono-therapies with either doxorubicin or radiation. These results support the use of the concomitant chemo-/radiation therapy for adjuvant treatment of FISS, particularly in advanced or recurrent disease where surgery alone is no longer feasible.     

Usefulness of the murine model to study the immune response against Histoplasma capsulatum infection

The present paper is an overview of the primary events that are associated with the histoplasmosis immune response in the murine model. Valuable data that have been recorded in the scientific literature have contributed to an improved understanding of the clinical course of this systemic mycosis, which is caused by the dimorphic fungus Histoplasma capsulatum. Data must be analyzed carefully, given that misinterpretation could be generated because most of the available information is based on experimental host–parasite interactions that used inappropriate proceedings, i.e., the non-natural route of infection with the parasitic and virulent fungal yeast-phase, which is not the usual infective phase of the etiological agent of this mycosis.     

A spatial risk assessment of bighorn sheep extirpation by grazing domestic sheep on public lands

Bighorn sheep currently occupy just 30% of their historic distribution, and persist in populations less than 5% as abundant overall as their early 19th century counterparts. Present-day recovery of bighorn sheep populations is in large part limited by periodic outbreaks of respiratory disease, which can be transmitted to bighorn sheep via contact with domestic sheep grazing in their vicinity. In order to assess the viability of bighorn sheep populations on the Payette National Forest (PNF) under several alternative proposals for domestic sheep grazing, we developed a series of interlinked models. Using telemetry and habitat data, we characterized herd home ranges and foray movements of bighorn sheep from their home ranges. Combining foray model movement estimates with known domestic sheep grazing areas (allotments), a Risk of Contact Model estimated bighorn sheep contact rates with domestic sheep allotments. Finally, we used demographic and epidemiologic data to construct population and disease transmission models (Disease Model), which we used to estimate bighorn sheep persistence under each alternative grazing scenario. Depending on the probability of disease transmission following interspecies contact, extirpation probabilities for the seven bighorn sheep herds examined here ranged from 20% to 100%. The Disease Model allowed us to assess the probabilities that varied domestic sheep management scenarios would support persistent populations of free-ranging bighorn sheep.